Amino Acids and the Spikes from the Retinal Ganglion Cells

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Science  05 May 1967:
Vol. 156, Issue 3775, pp. 648-650
DOI: 10.1126/science.156.3775.648


The effects of amino acids or mixtures of amino acids on the spike discharges from the optic ganglion cells were studied. Mixtures of amino acids have different effects than single amino acids. Proper composition of excitatory and inhibitory amino acids can enhance only the light-induced spikes without giving rise to any spontaneous discharges. It is implied that amino acids may play an important role in the regulation of the general sensitivity of cells in the central nervous system.