Plasma Membranes of Rat Liver: Isolation of Lipoprotein Macromolecules

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Science  05 May 1967:
Vol. 156, Issue 3775, pp. 665-667
DOI: 10.1126/science.156.3775.665


Three high-denisity lipoprotein classes and one protein were separated from rat-liver plasma in membranes that had been treated with mild sonic oscillation. The lipoproteinis were separated and identified by techniques in which ultracentrifugation was used. Enzyme markers and electron-microscopic examination revealed membrane preparations essentially free of contaminating cellular partictulates.