Cell-Bound Immunity to Autologous and Syngeneic Mouse Tumors Induced by Methylcholanthrene and Plastic Discs

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Science  19 May 1967:
Vol. 156, Issue 3777, pp. 981-983
DOI: 10.1126/science.156.3777.981


A colony-inhibition assay, was lused to demonstrate specific immunity in vitro against syngeneic mouse sarcomas induced by mlethlylcholanthrene or implanted Dictabelt plastic discs. An immunity to methylcholanthrene-induced tumors could also be demonstrated with lymphocytes derived from the autologous primary tumor-bearing host 3 to 8 days after removal of the primary tumor.