Cholinesterase in Plasma: First Reported Absence in the Bantu; Half-life Determination

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Science  30 Jun 1967:
Vol. 156, Issue 3783, pp. 1748-1750
DOI: 10.1126/science.156.3783.1748


A Bantu schoolgirl is the first non-Caucasoid found homozygous for the "silent" cholinesterase gene. Investigation of her family revealed two heterozygotes. The propositus possesses no antibody to normal cholinesterase. Transfused cholinesterase had in her a half-life of approximately 10 days.