Thyrocalcitonin: Evidence for Release in a Spontaneous Hypocalcemic Disorder

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Science  14 Jul 1967:
Vol. 157, Issue 3785, pp. 205-206
DOI: 10.1126/science.157.3785.205


Thyrocalcitonin content of thyroid gland extracts from normal postparturient cows was 3.9 times greater than in cows with postparturient paresis. The parafollicular cells in diseased cows were less numerous and appeared to have discharged their secretory products. An abrupt release of thyrocalcitonin near parturition may be related to the development of the hypocalcemia and hypophosphatemia in this disorder.