Antigenic Study of the Protein from a Defective Strain of Tobacco Mosaic Virus

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Science  14 Jul 1967:
Vol. 157, Issue 3785, pp. 207-208
DOI: 10.1126/science.157.3785.207


Soluble protein from the defective strain PM2 of tobacco mosaic virus can be recognized as antigenically distinct from the protein of the wild-type tobacco mosaic virus by Ouchterlony and immunoelectrophoretic analyses at temperatures below 37°C. At these temperatures a polymerized state of protein with a characteristic antigenic structure is present in the wild-type virus; this structure is absent from the PM2 preparations. Above 37°C the precipitin patterns for tobacco mosaic virus and PM2 appear identical.