Resistance Shifts Accompanying the Evoked Cortical Response in the Cat

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Science  14 Jul 1967:
Vol. 157, Issue 3785, pp. 211-213
DOI: 10.1126/science.157.3785.211


Clicks and flashes that evoke an electrical response from the auditory or visual cortex also evoke a resistance shift in the tissue. The resistance shift, a drop followed by a rise in resistance, closely follows the temporal pattern of the electrical response recorded simultaneously through the same electrodes. While several experimental manipulations produce corresponding changes in the amplitudes of both electrical response and resistance shift, the resistance shift is more sensitive to alterations in cortical temperature and anesthetic level. The two responses behave distinctly differently as a function of the depth of the electrode in the cortex.