Toxohormone from Normal Tissues

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Science  21 Jul 1967:
Vol. 157, Issue 3786, pp. 327-328
DOI: 10.1126/science.157.3786.327


The presence of toxohormone-like factor in autolysates of animal tissues was investigated. One could always isolate appreciable quantities of preparations having toxohormone activity. At the doses tested, no activity could be shown in preparations from nonautolyzed tissues. We suggest that autolysis phenomena may cause the presence of toxohormone in tumor-bearing organisms.