Chemoprophylactic Agent in Schistosomiasis: 14,15-Epoxygeranylgeraniol

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Science  25 Aug 1967:
Vol. 157, Issue 3791, pp. 950-951
DOI: 10.1126/science.157.3791.950


The occurrence of all-trans (-)-14,15-epoxygeranyl-geraniol in Pterodon pubescens Benth. is established, and its prophylactic activity against infection by Schitsosma mansoni demonstrated. Two other diterpenes present in the oil are inactive.