Immunoglobulin Structure: Variation in Amino Acid Sequence and Length of Human Lambda Light Chains

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Science  01 Sep 1967:
Vol. 157, Issue 3792, pp. 1050-1053
DOI: 10.1126/science.157.3792.1050


Variation and conservation in the primary structure of human lambda light chains is revealed by complete amino acid sequence of three Bence Jones proteins. These proteins differ in amino acid sequence in from 38 to 48 positions; they are of unequal length in the amino-terminal half of the chain but have identical sequence in the last 105 amino acids.