Eosinophilic Response in Glioblastoma Tissue Culture after Addition of Autologous Lymphocytes

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Science  01 Sep 1967:
Vol. 157, Issue 3792, pp. 1054-1055
DOI: 10.1126/science.157.3792.1054


In experiments designed for the study of interactions in vitro between the cells of glioblastoma multiforme and lymphocytes from the same donor, a marked eosinophilic response was noted in three out of six cases. This was an entirely unexpected finding since few, if any, eosinophils survive in tissue cultures. These cells incorporated 3H-cytidine and 3H-leucine 72 hours after the cultures had been established, an indication that they were metabolically active.