Heterophile Reactive Antigen in Infectious Mononucleosis

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Science  08 Sep 1967:
Vol. 157, Issue 3793, pp. 1200-1202
DOI: 10.1126/science.157.3793.1200


Specific heterophile reactive antigen has been localized by means of indirect immunofluorescence in 12 of 13 kidney biopsy specimens obtained during the acute phase of infectious mononucleosis. I feel that this may represent the identification of infectious agent antigen. Evidence is also presented for the possible existence of two different strains of the agent of infectious mononucleosis.