Mitochondrial Malate Dehydrogenase: A New Genetic Polymorphism in Man

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Science  29 Sep 1967:
Vol. 157, Issue 3796, pp. 1569-1571
DOI: 10.1126/science.157.3796.1569


Starch-gel electrophoresis patterns of malate dehydrogenase from human tissue indicate a new genetic polymorphism for the mitochondrial form of the enzyme. Studies of families showed simple Mendelian segregation rather than maternal inheritance, suggesting that not all mitochondrial proteins are coded by mitochondrial DNA.