Actinomycin D Effect on Amino Acid Absorption from Rat Jejunal Loops

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Science  06 Oct 1967:
Vol. 158, Issue 3797, pp. 129-130
DOI: 10.1126/science.158.3797.129


The absorption of amino acids from jejunal loops was suppressed in anesthetized rats treated previously with 1.0 or 1.5 micrograms of actinomycin D per gram of body weight. The absorption of the acidic, neutral, and basic amino acids showed selective differences in response that were relative to the degree of inhibition and to the time interval required to demonstrate actinomycin sensitivity.