Virus-Induced Peliosis Hepatis in Rats

Science  20 Oct 1967:
Vol. 158, Issue 3799, pp. 377-378
DOI: 10.1126/science.158.3799.377


Inoculation of newborn Fischer, W/Fu, or Lewis rats with the 9H virus recently isolated from leukemic rat tissues resulted in the development of peliosis hepatis. The virus was recoverable from the peliotic livers. The cystic lesions were of the parenchymal peliosis type and appeared to be the result of focal hepatic necrosis followed by hemorrhage.