Visceral Tissue Vascularization: An Adaptive Response to High Temperature

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Science  01 Dec 1967:
Vol. 158, Issue 3805, pp. 1203-1204
DOI: 10.1126/science.158.3805.1203


Electrical heat sources implanted in the abdominal cavities of sheep were heated to give initial temperatures of 42° and 45°C at the surfaces of the heaters. During 18 days of constant heating, a vascularized connective-tissue envelope encapsulated the heat sources, and the temperatures at the surfaces of the heaters declined 0.8° and 1.8°C, respectively. The degree of vascularization and the magnitude of the decrease in the surface temperature appeared to be related to the proximity of the tissue's initial temperature to 45°C, a temperature ordinarily considered detrimental to cell structure. The vascularization thus appears to be adaptive.