Transforming Activity of Green Monkey SA7 (C8) Adenovirus in Tissue Culture

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Science  15 Dec 1967:
Vol. 158, Issue 3807, pp. 1455-1457
DOI: 10.1126/science.158.3807.1455


Simian SA7 (C8) adenovirus can effect transformation of mouse, rat, and hamster cells in tissue culture. The transforming activity of the virus was more pronounced in culture medium containing 0.1 millimolar CaCl2, a lower concentration than that usually used. The transformed hamster cells were tumorigenic in hamsters.