Biochemical Genetics of Oxidative Phosphorylation

Science  22 Dec 1967:
Vol. 158, Issue 3808, pp. 1564-1567
DOI: 10.1126/science.158.3808.1564


The usefulness of mutants in the unraveling of complex, highly organized, membrane-bound processes such as oxidative phosphorylation is illustrated by a study of a single recessive gene mutation in yeast, designated op1, which has abolished the efficiency in vivo and in vitro of oxidative phosphorylation without impairing the electron transfer.