Renin-Like Enzyme in the Adrenal Gland

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Science  22 Dec 1967:
Vol. 158, Issue 3808, pp. 1589-1590
DOI: 10.1126/science.158.3808.1589


The rabbit adrenal gland contains an enzyme which reacts with renin substrate to form a vasopressor polypeptide, probably angiotensin I. In view of the strong effects of angiotensin on secretion of aldosterone and catecholamine, this finding suggests that there may be an intra-adrenal mechanism for the control of adrenal secretions.