Increased Turnover of Cerebral Norepinephrine during Rebound of Paradoxical Sleep in the Rat

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Science  05 Jan 1968:
Vol. 159, Issue 3810, pp. 112-114
DOI: 10.1126/science.159.3810.112


Changes in turnover of cerebral norepinephrine, as measured after intracisternal administration of the H3 amine, have been studied in rats during selective paradoxical sleep deprivation and its following rebound. Experiments were performed under neurophysiological control. A marked increase of turnover of norepinephrine is associated with the augmentation of paradoxical sleep characteristic of the rebound period.