Amnesia: A Function of the Temporal Relation of Footshock to Electroconvulsive Shock

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Science  12 Jan 1968:
Vol. 159, Issue 3811, pp. 219-221
DOI: 10.1126/science.159.3811.219


When rats received a brief footshock upon stepping off an elevated platform, and an electroconvulsive shock 30 seconds or 6 hours afterward, amnesia was not observed 24 hours later. If a second footshock (noncontingent) was delivered 0.5 second before the electroconvulsive shock, amnesia was observed. The amnesia was temporary if conditioning was strong and permanent if conditioning was weak.