Ethanol-1-C14 Metabolism in Alcoholics and Nonalcoholics

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Science  19 Jan 1968:
Vol. 159, Issue 3812, pp. 319-320
DOI: 10.1126/science.159.3812.319


Metabolism of ethanol-1-C14 was assessed in a group of alcoholic and nonalcoholic male subjects. All subjects were screened for absence of physical derangement. Subjects were also carefully matched by dietary, social, and environmental criteria. No differences in rate of output of Cl4CO2 were detected after ingestion of alcohol which produced concentrations of 50 to 60 milligrams of alcohol per 100 milliliters of blood. These data do not support the hypothesis that alcoholics metabolize ethanol more rapidly than nonalcoholics do.