Lysergic Acid Diethylamide (LSD): No Teratogenicity in Rats

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Science  16 Feb 1968:
Vol. 159, Issue 3816, pp. 731-732
DOI: 10.1126/science.159.3816.731


Lysergic acid diethylamide (LSD) in doses of 1.5 to 300 micrograms was given to 55 pregnant rats during periods of organogenesis and on the 4th or 5th day of pregnancy to 34 rats. Examination of the resultant 887 young for congenital defects showed no greater frequency than in controls. These experimtents failed to prove that LSD is teratogenic in rats.