Sulfur-Containing Nucleoside from Yeast Transfer Ribonucleic Acid: 2-Thio-5(or 6)-uridine Acetic Acid Methyl Ester

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Science  29 Mar 1968:
Vol. 159, Issue 3822, pp. 1481-1483
DOI: 10.1126/science.159.3822.1481


A nucleoside, isolated from yeast transfer RNA, has been assigned the structure 2-thio-5-uridine acetic acid methyl ester on the basis of high-esolution mass spectrometry, chemical properties, and ultraviolet spectra. The alternate 6-substituted isomeric structure cannot yet be completely ruled out.