Estrogen Induces Lipophosphoprotein in Serum of Male Xenopus laevis

See allHide authors and affiliations

Science  05 Apr 1968:
Vol. 160, Issue 3823, pp. 91-92
DOI: 10.1126/science.160.3823.91


Administration of estradiol 17β to male Xenopus laevis induces the appearance in serum of large amounts of a serum lipophosphoprotein which is not readily removed from the circulation and which can be resolved from other serum components by chromatography on triethylaminoethyl-cellulose. The initial rate of production of serum lipophosphoprotein is independent of the amount of estrogen administered, but the maximum rate of production and the time taken to attain this rate are dose-dependent.