Reports

Neonatal Castration: Influence on Neural Organization of Sexual Reflexes in Male Rats

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Science  07 Jun 1968:
Vol. 160, Issue 3832, pp. 1135-1136
DOI: 10.1126/science.160.3832.1135

Abstract

Most male rats castrated 4 days after birth and given exogenous testosterone in adulthood were sexually motivated but incapable of completing the mating sequence with an ejaculatory response. When tested for sexual reflexes after spinal transection, these animals displayed impairment of genital responses. Similarly treated 12-day castrates exhibited a complete mating sequence and had normal sexual reflexes. Thus neonatal testicular androgen appears to have an organizational influence at the spinal level on neural tissue mediating sexual reflexes.