Falciparum Malaria Transmissible from Monkey to Man by Mosquito Bite

Science  05 Jul 1968:
Vol. 161, Issue 3836, pp. 56
DOI: 10.1126/science.161.3836.56


Anopheles freeborni mosquitoes were infected by feeding on a New World monkey, Aotus trivirgatus, infected with the Malayan IV strain of Plasmodium falciparum. After a normal incubation period, the infection was passed to a human volunteer through the bites of these mosquitoes, demonstrating for the first time the practicability of using a simian host as a donor for the infection of mosquitoes with this species of human malarial parasites.