Molecular Aspects of Specific Cell Contact

Science  02 Aug 1968:
Vol. 161, Issue 3840, pp. 473-475
DOI: 10.1126/science.161.3840.473


Complementary macromolecules were isolated from yeasts of opposite mating type. These cell-surface molecules neutralize each other as do antibodies and antigens. Both yeast factors are glycoproteins of low molecular weight. Other specific cell associations may be due to the interaction of such complementary macromolecules.