Reports

5-Ethyldeoxyuridine, a Thymidine Analog: Photochemical Transformation

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Science  20 Sep 1968:
Vol. 161, Issue 3847, pp. 1248-1249
DOI: 10.1126/science.161.3847.1248

Abstract

Irradiation at 254 millimicrons transforms 5-ethyldeoxyuridine to deoxyuridine by way of photohydration of the 5,6 bond and elimination of ethanol. At wavelengths to the red side of 265 millimicrons, photodimerization is the principal reaction, with a pronounced oxygen effect. The results are related to the photochemistry of thymidine and of bacteriophages containing incorporated 5-ethyluracil in place of thymine.