Reports

Electrotonic Spread of Dendritic Potentials in Feline Pyramidal Cells

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Science  27 Sep 1968:
Vol. 161, Issue 3848, pp. 1351-1353
DOI: 10.1126/science.161.3848.1351

Abstract

In pyramidal cells synaptic activation of the entire apical dendritic tree distal to the branch point of the major shaft can dominate the neuronal firing pattern. Uniform synaptic activation of distant parts of the dendritic tree (~ 750 microns from the soma) would produce potential changes at the soma of 2 to 3 percent of the magnitude of the dendritic potential changes. Even these small somatic potential changes could modulate the frequency of firing of neurons depolarized close to or above firing level by more proximal synaptic inputs.

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