Reports

Frame Shift Mutations near the Beginning of the Lysozyme Gene of Bacteriophage T4

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Science  15 Nov 1968:
Vol. 162, Issue 3855, pp. 807-808
DOI: 10.1126/science.162.3855.807

Abstract

A pair of frame shift mutations in the lysozyme gene of bacteriophage T4 results in the substitution of a glutamyl-tyrosyl sequence for the asparagine residue that is the penultimate amino-terminal amino acid in the lysozyme of the wild-type strain. One of the mutations has been identified as the insertion of two bases, the other as the insertion of a single base.