Intellectual Deficit Associated with Transplacentally Induced Microcephaly in the Rat

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Science  03 Jan 1969:
Vol. 163, Issue 3862, pp. 88-90
DOI: 10.1126/science.163.3862.88


Fischer rats injected with methylazoxymethanol late in pregnancy produce young with considerably reduced cerebral hemispheres. They appear normal otherwise. As adults these animals make many more errors in the Hebb-Williams maze than do control animals.