Reports

Monosodium L-Glutamate: Its Pharmacology and Role in the Chinese Restaurant Syndrome

Science  21 Feb 1969:
Vol. 163, Issue 3869, pp. 826-828
DOI: 10.1126/science.163.3869.826

Abstract

Monosodium L-glutamate is the cause of the Chinese restaurant syndrome and can precipitate headaches. In appropriate doses it causes burning sensations, facial pressure, and chest pain. These are pharmacological effects obeying a dose-effect relationship. There is considerable variation in oral threshold does among individuals.

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