Purines: Active Transport by Isolated Choroid Plexus

Science  14 Mar 1969:
Vol. 163, Issue 3872, pp. 1194-1195
DOI: 10.1126/science.163.3872.1194


Purines are actively accumulated by the isolated rabbit choroid plexus by a specific saturable transport mechanism. In vivo this system probably serves to excrete the purine catabolities of brain from cerebrospinal fluid into blood.