Pulmonary Gas Transport Time: Larynx to Alveolus

Science  14 Mar 1969:
Vol. 163, Issue 3872, pp. 1210-1211
DOI: 10.1126/science.163.3872.1210


The transport time of gas from the larynx to pulmonary alveolar capillary blood was directly measured by injecting a bolus of carbon monoxide into the inspired airstream of dogs and photoelectrically monitoring the formation of carboxyhemoglobin in the capillaries on the surface of the lung. The rapidity of transit (0.3 second) implies that gas transport during inspiration is facilitated by an interaction between bulk flow and diffusion.