Dihydroorotic Acid Dehydrogenase: Introduction into Erythrocyte by the Malaria Parasite

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Science  30 May 1969:
Vol. 164, Issue 3883, pp. 1073-1075
DOI: 10.1126/science.164.3883.1073


Mature, circulating mammalian erythrocytes lack dihydroorotic acid dehydrogenase activity. However, we have detected activity, which appears to reside in an enzyme, in malaria parasites purified from mammalian blood.