Relation of Pharmacological and Behavioral Effects of a Hallucinogenic Amphetamine to Distribution in Cat Brain

Science  30 May 1969:
Vol. 164, Issue 3883, pp. 1085-1087
DOI: 10.1126/science.164.3883.1085


The hallucinogen 2,5-dimethoxy,-4-methylamphetamine, also known as STP, accumulates in specfic areas of cat brains. The unchanged compound was detected in the brain for at least 6 hours, whereas its behavioral effects lasted for about 4 hourS. The coincidental pharmacological and behavioral effects of the compound apparently indicate a relation between the anatomical distribution and action.