Reports

Human Growth Hormone Release: Relation to Slow-Wave Sleep and Sleep-Waking Cycles

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Science  01 Aug 1969:
Vol. 165, Issue 3892, pp. 513-515
DOI: 10.1126/science.165.3892.513

Abstract

Release of human growth hormone during sleep is significantly related to slow, synchronized stages of sleep and therefore would seem to be controlled by related neural mechanisms. When sleep-waking cycles are reversed by 12 hours, the release of growth hormone with sleep is reversed; thus release does not follow an inherent circadian rhythm independent of sleep.