Genetic Coding: Oligonucleotide Coding for First Six Amino Acid Residues of the Coat Protein of R17 Bacteriophage

Science  05 Dec 1969:
Vol. 166, Issue 3910, pp. 1291-1293
DOI: 10.1126/science.166.3910.1291


Ribonucleic acids from the bacteriophage R17 and from R17 amber mutant AmB2 have been digested with ribonuclease T1. Of the products isolated, only one was different. It codes for the first six amino acid residues of theviral coat protein. The probable base sequence of the wild-type oligonucleotide is CpUpUpCpUpApApCpUpUpUpApCpUpCpApGp.