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Mitochondrial RNA Synthesis during Mitosis

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Science  03 Apr 1970:
Vol. 168, Issue 3927, pp. 135-138
DOI: 10.1126/science.168.3927.135

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Abstract

HeLa cells arrested in metaphase synthesized relatively normal amounts of mitochondrial RNA, while little RNA synthesis associated with the nucleus was detected. The RNA synthesized resembled the portion of mitochondrial RNA sensitive to ethidium bromide in interphase cells, with major peaks at 21, 12, and 4S. Unlike that in interphase cells, RNA synthesis in the mitoclhonidrial fraction of mitotic cells was completely inhibited by ethidium bromide.