Antimycin A: Stimulation of Cell Division and Protein Synthesis in Tetrahymena pyriformis

Science  17 Apr 1970:
Vol. 168, Issue 3929, pp. 385-386
DOI: 10.1126/science.168.3929.385


Addition of antimycin A to a culture of Tetrahymena pyriformis caused an increase in cell division and protein synthesis in this ciliated protozoan. The antimycin effect is a function of the time of exposure to the antibiotic as well as of the age of the culture. A large accumulation of endoplasmic reticulum, reflecting increased protein synthesis, was visualized by electron microscopy in cells stimulated by the antimycin A.