"Hypersexuality" and Behavioral Changes in Cats Caused by Administration of p-Chlorophenylalanine

Science  24 Apr 1970:
Vol. 168, Issue 3930, pp. 499-501
DOI: 10.1126/science.168.3930.499


The behavior of 26 male cats was systematically observed before, during, and after daily administration of the tryptophan hydroxylase inhibitor, p-chlorophenylalanine. These observations established that "hypersexuality," increased aggression, and perceptual disorientation are sequelae of the chronic administration of the drug in cats.