Reports

Somatic Cell Mating and Segregation in Chimeric Frogs

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Science  15 May 1970:
Vol. 168, Issue 3933, pp. 850-852
DOI: 10.1126/science.168.3933.850

Abstract

Both pentaploid and haploid cells were observed in a short-term culture of bone marrow of a diploid-triploid frog chimera. Apparently, diploid and triploid marrow cells fused to form "hybrid" pentaploid cells, which subsequently gave rise by somatic reduction to haploid daughter cells. The hybrid marrow cells and their haploid segregants are presumably at a selective disadvantage, as neither type of cell has been detected in the circulating blood of chimeric frogs.

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