Saccharomyces cerevisiae: A Diffusible Sex Factor

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Science  19 Jun 1970:
Vol. 168, Issue 3938, pp. 1472-1473
DOI: 10.1126/science.168.3938.1472


A hormone-like substance is secreted by α mating-type cells of heterothallic yeast strains. It induces in cells of the opposite mating type, a, a morphological change characteristic of the mating process. Secretion of this substance and mating ability have some common genetic determinants. In partially purified preparations, the substance has properties of an oligopeptide.