Trisponic Acid Synthesis in Blakeslea trispora

Science  26 Jun 1970:
Vol. 168, Issue 3939, pp. 1590-1592
DOI: 10.1126/science.168.3939.1590


Cultures of the (-) strain of Blakeslea trispora synthesize trisporic acid C, a sex hormone, from precursors made by cultures of the (+) strain. The precursors are nonacidic compounds isolated from the culture medium of the (+) strain by chloroform extraction. Actidione does not inhibit trisporic acid synthesis from isolated precursors, suggesting that the enzymes involved in the synthesis in cultures of the (-) strain are constitutive.