Homozygous Hb J Tongariki: Evidence for Only One Alpha Chain Structural Locus in Melanesians

Science  10 Jul 1970:
Vol. 169, Issue 3941, pp. 194-196
DOI: 10.1126/science.169.3941.194


A high frequency of Hb J Tongariki (α 115 Ala → Asp) was found in a Kilenge village in New Britain. Heterozygotes had 45 to 50 percent of the Hb J component (determined by cellulose acetate electrophoresis). Two homozygotes for Hb J had no Hb A, suggesting that in this family only one Hbα structural locus is present.