Pituitary Serotonin Content: Effects of Melatonin or Deprivation of Water

Science  17 Jul 1970:
Vol. 169, Issue 3942, pp. 285-286
DOI: 10.1126/science.169.3942.285


Relatively high concentrations of serotonin are found in the three regions of the rat pituitary gland. Administration of melatonin causes a selective increase in the serotonin concentration of the pars intermedia; deprivation of water for 5 days causes a selective decrease in the serotonin concentrations of the neural lobe and pars distalis.