Reports

Demyelinating Encephalomyelopathy Associated with Lead Poisoning in Nonhuman Primates

Science  11 Sep 1970:
Vol. 169, Issue 3950, pp. 1091-1093
DOI: 10.1126/science.169.3950.1091

Abstract

Lead poisoning was diagnosed in four primates by the finding of toxic amounts of lead in tissues. Abnormalities in the brain and spinal cord were characterized by vascular lesions and demyelination. These findings suggest a new animal model for the study of demyelination and strengthen the supposition that lead may be a factor in some idiopathic demyelinating diseases.

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