Reports

Specificity of Antigen Recognition by Human Lymphocytes in vitro

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Science  25 Dec 1970:
Vol. 170, Issue 3965, pp. 1404-1406
DOI: 10.1126/science.170.3965.1404

Abstract

Delayed hypersensitivity reactions in vivo are exquisitely specific, in terms of both a lack of response after induction of tolerance and a response after sensitization. These studies in vitro demonstrate that this specificity, at least at the level of antigen recognition, is probably derived from different populations of cells, each responding to different antigens.