Pulmonary Compliance: Alteration during Infection

Science  08 Jan 1971:
Vol. 171, Issue 3966, pp. 66-68
DOI: 10.1126/science.171.3966.66


Lungs excised from rats infected with Mycoplasma pulmonis are more difficult to inflate with air than those from uninfected animals; they show no significant differences from controls inflated with saline. The altered pulmonary function in lungs from infected rats is attributed to an increase in surface forces, implying disruption of the lung surfactant system.